Tony Hunter: Kinase king
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چکیده
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Tony Hunter: Kinase king
B efore 1979, kinases were only thought to stick phosphates on two of the twenty amino acids: serine and threonine. But then Tony Hunter discovered that tyrosine could also be phosphorylated (1, 2), thereby uncovering an entirely new mechanism of protein regulation in cells. Since then, Hunter has worked on all sorts of protein phos-phorylation events and the kinases that deliver them. Indeed, ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2008
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1814pi